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Infertility in Men Despite some mixed findings, most clinical studies suggest that L-carnitine increases sperm count and sperm motility in men with infertility [19, 20, 21]

Moreover, in enteroendocrine L cells of the gut, indole stimulates the secretion of incretin glucagon-like peptide-1 (GLP-1), which increases insulin secretion, suppresses appetite, and slows gastric emptying [111]

Current publications have shown that interventions, such as dietary management, intestinal flora regulation, the inhibition of TMAO precursor production, the prevention of TMA transformation, fecal flora transplantation, and treatment with medicine or traditional Chinese medicine, can prevent and treat AS

Glucocorticoids such as prednisone are used to treat difficult cases that do not respond adequately to first-line pharmacologic or other treatments